Sildenafil Oral Jelly 100mg typically starts to take effect within 30 to 60 minutes after consumption. However, the exact timing can vary depending on individual factors like metabolism, diet, and overall health. For the best results, it's usually recommended to take it on an empty stomach or with a light meal, as heavy or fatty foods can slow down its absorption. If you have any concerns or experience unexpected effects, it's a good idea to consult with your healthcare provider.