Vidalista 60mg, like other PDE-5 inhibitors, works by increasing blood flow to the penis. During sexual arousal, nitric oxide is released in the body, which activates an enzyme called guanylate cyclase. This enzyme is responsible for producing cyclic guanosine monophosphate (cGMP), which relaxes the smooth muscles in the blood vessels of the penis, allowing for increased blood flow. However, an enzyme called phosphodiesterase type 5 (PDE-5) breaks down cGMP, leading to a decrease in blood flow and the inability to maintain an erection.
Tadalafil, the active ingredient in Vidalista 60, inhibits the action of PDE-5. By doing so, it allows cGMP levels to remain elevated, resulting in improved blood flow to the penis. This enhanced blood flow helps men achieve and sustain a firm erection, making it possible to engage in sexual activity.