Farm Diablo 4 Shard of Agony fast from Grigoire and Varshan, then cash it in for repeat Duriel runs in the Gaping Crevasse to chase Uber uniques without wasting mats.
If you're chasing Uber Uniques in Diablo 4, you already know the bottleneck isn't damage, it's keys. Shards of Agony are the thing that decides whether you're doing real Duriel runs tonight or just pacing around town checking your stash. Some players even top up supplies outside the game so they can stay on their farming loop, and sites like
EZNPC are often mentioned for picking up game currency or items when time's tight and you'd rather be fighting than shopping Helltides.
Where Shards Actually Come From
Most of your shards come from other endgame bosses, and the usual path is pretty straightforward. Grigoire, the Galvanic Saint, is the main one because he's tied to Living Steel. You grab Steel from Helltide chests and whatever endgame activities your season is pushing, then you cash it in for Grigoire kills. Echo of Varshan can help too if you've got the parts sitting around from normal play. And lately, Blizzard's been a bit more generous—world bosses and certain seasonal or DLC activities can also drip-feed shards, but the consistency usually isn't there compared to boss farming.
A Fast Farming Loop That Doesn't Feel Like a Chore
If you want speed, you plan your session around materials, not vibes. First, do a focused Living Steel run: pick a Helltide window, hit the right chests, don't get distracted. Second, turn that Steel into a string of Grigoire summons. Third, if you've got friends, rotate materials so everybody gets more pulls per hour—this is where your shard pile starts to look real. If you own Vessel of Hatred, the Undercity can be worth weaving in, especially when you can use the right Tributes to nudge drops toward boss keys. It's not magic, but it breaks up the monotony and still moves the needle.
When to Spend Them on Duriel
Once shards are in your pocket, you're basically booking a ticket to the Gaping Crevasse in Kehjistan. Depending on the season, you'll either use Shards of Agony with other materials to summon Duriel, or you'll use them as part of the reward flow after the fight. Either way, don't rush it. Duriel's poison can delete you if your resists are sloppy or your build's missing sustain. A lot of people waste keys trying to "see if it's fine." It's rarely fine. Get your defenses sorted, then farm him on a tier you can clear clean.
Making the Grind Worth It
The best feeling is when your runs stop being stressful and start being automatic—pull, kill, loot, repeat. That's when shards turn into real chances at Mythic drops instead of random gamble tokens. Keep your loop simple, bank enough for a proper streak of attempts, and don't be afraid to prep ahead so your playtime is actually spent in fights; some folks even grab extra resources like Diablo 4 Gold so they can keep rolling without pausing to rebuild their stack.